Diagnostic and prognostic value of the Creatinine/Cystatin C ratio for low muscle mass evaluation among US adults.

ABSTRACT:

Background

Identifying patients with low muscle mass is crucial for the diagnosis of sarcopenia. Although the Creatinine/Cystatin C (Cr/CysC) is recommended as a simplified indicator to identify patients with low muscle mass, its ability to assess muscle mass and predict a poor prognosis has not been validated. We aimed to determine the diagnosis value of Cr/CysC for low muscle mass and examine the association of Cr/CysC with mortality.

Methods

In this cohort study we analyzed data from the National Health and Nutrition Examination Survey from 1999 to 2002. Follow-up was conducted up to December, 2015. Appendicular skeletal mass was calculated based on dual-energy X-ray absorptiometry (DXA) scans. Low muscle mass was defined referring to five international diagnostic criteri

SUBMITTER: Shi S 

PROVIDER: S-EPMC9398338 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature