Both-Ear Method for the Analysis of Audiometric Data.

ABSTRACT:

Objective

Single-ear hearing measurements, such as better-ear, worse-ear or left/right ear, are often used as outcomes in auditory research, yet, measurements in the two ears of the same individual are often strongly but not perfectly correlated. We propose a both-ear method using the Generalized Estimating Equation approach for analysis of correlated binary ear data to evaluate determinants of ear-specific outcomes that includes information from both ears of the same individual.

Design

We first theoretically evaluated bias in odds ratio (OR) estimates based on worse-ear and better-ear hearing outcomes. A simulation study was conducted to compare the finite sample performances of single-ear and both-ear methods in logistic regression models. As an illustrative example, the s

SUBMITTER: Chen C 

PROVIDER: S-EPMC9398921 | biostudies-literature | 2022 Sep-Oct 01

REPOSITORIES: biostudies-literature