A Cost-effectiveness Analysis of Adherence Promotion Strategies to Improve Rejection Rates in Adolescent Kidney Transplant Recipients.

ABSTRACT:

Rationale & objective

Nonadherence to medical regimens increases the risk of graft loss among adolescent and young adult recipients of kidney transplants. Interventions that improve adherence may decrease rejection rates, but their perceived costs are a barrier to clinical implementation. We developed a model to assess the cost-effectiveness of an adherence promotion strategy, the Medication Adherence Promotion System (MAPS).

Study design

Simulation-based. Data sources included published articles indexed in Medline or referenced in bibliographies of relevant English-language articles. Data on costs and outcomes were taken from a single clinical center.

Setting & population

US adolescent patients after their first kidney transplant.

Intervention

Usual posttransp

SUBMITTER: Varnell CD 

PROVIDER: S-EPMC9398956 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature