Crystal polymorphism and spectroscopical properties of sulfonamides in solid state by means of First Principles calculations.

ABSTRACT: Sulfonamides are an important class of therapeutic agents. The increase in the number of new sulfonamide derivatives makes it necessary to study more rationally the chemical structure, because the solid forms often display different mechanical, thermal and physicochemical properties that can influence the bioavailability and stability of the drugs; consequently, the polymorphic structures are of great interest to the pharmaceutical industry because of their ability to modify the physical properties of the active pharmaceutical ingredient. The molecular interactions of these drugs in their crystal lattice are important for the stability of the crystals and polymorphism and for preparing composite complexes for optimizing the use of these drugs. In this work, the crystal structure of these d

SUBMITTER: Sainz-Diaz CI 

PROVIDER: S-EPMC9399194 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature