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Design, preparation and application of the semicarbazide-pyridoyl-sulfonic acid-based nanocatalyst for the synthesis of pyranopyrazoles.

ABSTRACT: A novel, efficient, and recoverable nanomagnetic catalyst bearing the semicarbazide linkers, namely, Fe₃O₄@SiO₂@OSi(CH₂)₃-N(3-pyridoyl sulfonic acid)semicarbazide (FSiPSS) was designed, synthesized and characterized by the use of various techniques such as FT-IR, EDX, elemental mapping analysis, XRD, SEM, TEM, TGA/DTA, BET, and VSM. Then, the catalytic capability of the novel prepared nanomagnetic FSiPSS catalyst was successfully investigated in the synthesis of diverse pyranopyrazoles through a one-pot four-component condensation reaction of ethyl acetoacetate, hydrazine hydrate, aromatic aldehydes, and malononitrile or ethyl cyano-acetate by the help of ultrasonication in very short reaction time, good to high yields and easy work-up (Fig. 1). Figure 1 Synthesis of diverse pyranopyrazoles by the FSiPSS nano-catalyst.

SUBMITTER: Beiranvand M

PROVIDER: S-EPMC9399233 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Design, preparation and application of the semicarbazide-pyridoyl-sulfonic acid-based nanocatalyst for the synthesis of pyranopyrazoles.

Beiranvand Masoumeh M Habibi Davood D

Scientific reports 20220823 1

A novel, efficient, and recoverable nanomagnetic catalyst bearing the semicarbazide linkers, namely, Fe3O4@SiO2@OSi(CH2)3-N(3-pyridoyl sulfonic acid)semicarbazide (FSiPSS) was designed, synthesized and characterized by the use of various techniques such as FT-IR, EDX, elemental mapping analysis, XRD, SEM, TEM, TGA/DTA, BET, and VSM. Then, the catalytic capability of the novel prepared nanomagnetic FSiPSS catalyst was successfully investigate ...[more]

PMID: 35999336

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