Efficacy and safety of pembrolizumab on cervical cancer: A systematic review and single-arm meta-analysis.

ABSTRACT:

Background

According to current research, the objective response rate and overall survival of pembrolizumab in the treatment of several types of solid tumors have been significantly improved. Some high-quality clinical trials have studied the effect of applying pembrolizumab in treating cervical cancer. Multiple clinical trials have been conducted, and some of them have shown good results as expected. Therefore, we performed this meta-analysis on existing studies to reveal the efficacy and safety of pembrolizumab in treating cervical cancer.

Methods

PubMed, Embase, Cochrane Library and Web of Science were searched for literatures published until October 31, 2021. Outcomes included complete response (CR), partial response (PR), stable disease (SD), disease progression (PD), o

SUBMITTER: Qi L 

PROVIDER: S-EPMC9399507 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature