Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms

ABSTRACT: The circadian rhythm is crucial for physiological and behavioral functions. Chronotype, which represents individual preferences for activity and performance, is associated with human health issues, particularly psychiatric disorders. This narrative review, which focuses on the relationship between chronotype and mental disorders, provides an insight into the potential mechanism. Recent evidence indicates that (1) the evening chronotype is a risk factor for depressive disorders and substance use disorders, whereas the morning chronotype is a protective factor. (2) Evening chronotype individuals with bipolar disorder tend to have more severe symptoms and comorbidities. (3) The evening chronotype is only related to anxiety symptoms. (4) The relationship between chronotype and schizophrenia re

SUBMITTER: Zou H 

PROVIDER: S-EPMC9399511 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature