Association Between Vitamin D Supplementation and Fall Prevention

ABSTRACT:

Background

Falls occur frequently among older individuals, leading to high morbidity and mortality. This study was to assess the efficacy of vitamin D in preventing older individuals from falling.

Methods

We searched the PubMed, Cochrane Library, and EMBASE databases systematically using the keywords “vitamin D” and “fall” for randomized controlled trials (RCTs) comparing the effects of vitamin D with or without calcium supplements with those of a placebo or no treatment on fall incidence in adults older than 50 years. A meta-analysis was performed to calculate risk ratios (RRs), absolute risk differences (ARDs) and 95% CIs with random-effects models.

Results

A total of 38 RCTs involving 61 350 participants fulfilled the inclusion criteria. Compared with placebo,

SUBMITTER: Wei F 

PROVIDER: S-EPMC9399608 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature