Digestibility of wheat alpha-amylase/trypsin inhibitors using a caricain digestive supplement.

ABSTRACT: Wheat is a major source of nutrition, though in susceptible people it can elicit inappropriate immune responses. Wheat allergy and non-celiac wheat sensitivity are caused by various wheat proteins, including alpha-amylase trypsin inhibitors (ATIs). These proteins, like the gluten proteins which can cause celiac disease, are incompletely digested in the stomach such that immunogenic epitopes reach the lower digestive system where they elicit the undesirable immune response. The only completely effective treatment for these immune reactions is to eliminate the food trigger from the diet, though inadvertent or accidental consumption can still cause debilitating symptoms in susceptible people. One approach used is to prevent the causal proteins from provoking an immune reaction by enhancing th

SUBMITTER: Juhasz A 

PROVIDER: S-EPMC9399795 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature