Negative prognostic impact of electrolyte disorders in patients hospitalized for Covid-19 in a large multicenter study.

ABSTRACT:

Background

The prognostic impact of electrolyte disorders in hospitalized COVID-19 patients is unclear.

Methods

The study included all adult patients hospitalized for COVID-19 in four hospitals in Northern Italy between January 2020 and May 2021 with at least one serum potassium and sodium measurement performed within 3 days since admission. Primary outcome was in-hospital death; secondary outcome was Intensive Care Unit (ICU) admission. A cause-specific Cox proportional-hazards regression model was used for investigating the association between potassium and sodium (as either categorical or continuous variables) and mortality or admission to ICU.

Results

Analyses included 3,418 adult hospitalized COVID-19 patients. At multivariable analysis, both hyperkalemia (Hazard

SUBMITTER: Genovesi S 

PROVIDER: S-EPMC9400003 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature