The mediating role of maternal metabolites between lipids and adverse pregnancy outcomes of gestational diabetes mellitus.

ABSTRACT: Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy, and the demographics of pregnant women have changed in recent decades. GDM is a metabolic disease with short- and long-term adverse effects on both pregnant women and newborns. The metabolic changes and corresponding risk factors should be of great significance in understanding the pathological mechanism of GDM and reducing the incidence of adverse pregnancy outcomes in patients with GDM. The well-known GDM-associated lipids used in clinical tests, such as triglyceride (TG), are thought to play a major role in metabolic changes during GDM, which have a potential causal relationship with abnormal pregnancy outcomes of GDM. Therefore, this study analyzed the relationship between clinical lipid indicator

SUBMITTER: Luo M 

PROVIDER: S-EPMC9400014 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature