Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study.

ABSTRACT:

Background

Age and ethnicity are among several factors that influence overall survival (OS) in ovarian cancer. The study objective was to determine whether ethnicity and age were of prognostic significance in women enrolled in a clinical trial evaluating the addition of bevacizumab to front-line therapy.

Methods

Women with advanced stage ovarian, primary peritoneal, or fallopian tube cancer were enrolled in a phase III clinical trial. All women had surgical staging and received adjuvant chemotherapy with one of three regimens. Cox proportional hazards models were used to evaluate the relationship between OS with age and race/ethnicity among the study participants.

Results

One-thousand-eight-hundred-seventy-three women were enrolled in the study. There were 280 minorit

SUBMITTER: duPont NC 

PROVIDER: S-EPMC9400113 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature