Diffusion spectrum imaging of patients with middle cerebral artery stenosis.

ABSTRACT:

Objective

We aimed to detect microstructural changes in the brains of patients with unilateral middle cerebral artery (MCA) stenosis and to assess the integrity of the fiber structure and the small-world networks using diffusion spectrum imaging (DSI).

Methods

A total of 21 healthy controls and 48 patients with unilateral MCA stenosis underwent 3.0 T MRI examination using DSI technique. Differential tractography, diffusion connectometry, and structural networks were performed by using DSI software. The correlation between the stenosis and quantitative anisotropy (QA) were analyzed using multiple regression models in the correlation tractography.

Results

Differential tractography analysis showed that the left or right MCA stenosis group had decreased fiber connectivity

SUBMITTER: Wan X 

PROVIDER: S-EPMC9400121 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature