Interaction between serum cotinine and body mass index on asthma in the children: a cross-sectional study.

ABSTRACT:

Background

The purpose of this study was to explore the interaction between serum cotinine (a marker of environmental tobacco smoke exposure) and body mass index (BMI) on asthma in children.

Methods

This cross-sectional study relied on representative samples of American children included in the National Health and Nutrition Examination Survey in 1999-2018. Multivariate logistic regression analyses were to evaluate the association between serum cotinine level, BMI z-score and asthma. Serum cotinine was dichotomized at 0.0436 ng/mL. Interactions were examined by the estimated joint effect of BMI and serum cotinine levels. We also performed interaction analyses in age and ethnicity subgroups.

Results

Among the 11,504 children aged 3 to 12 years included in the analysis,

SUBMITTER: He L 

PROVIDER: S-EPMC9400283 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature