Association of the cumulative triglyceride-glucose index with major adverse cardiovascular events in patients with type 2 diabetes.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and is associated with major adverse cardiovascular events (MACEs) in patients with type 2 diabetes mellitus (T2DM). However, the long-term effect of the TyG index on the incidence of MACEs remains unclear. We aimed to investigate the association between the cumulative TyG index and the risk of MACEs in patients with T2DM.

Methods

This post-hoc analysis of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial assessed patients' (T2DM > 3 months) cumulative TyG index and MACE data from the study database. Five fasting blood glucose and triglyceride measurements, at baseline and the first four visits, were taken from 5695 participants who had not experienced MACE

SUBMITTER: Tai S 

PROVIDER: S-EPMC9400318 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature