Metal-Free N-H Bond Activation by Phospha-Wittig Reagents.

ABSTRACT: N-containing molecules are mostly derived from ammonia (NH₃ ). Ammonia activation has been demonstrated for single transition metal centers as well as for low-valent main group species. Phosphinidenes, mono-valent phosphorus species, can be stabilized by phosphines, giving so-called phosphanylidenephosphoranes of the type RP(PR'₃ ). We demonstrate the facile, metal-free NH₃ activation using ArP(PMe₃ ), affording for the first time isolable secondary aminophosphines ArP(H)NH₂ . DFT studies reveal that two molecules of NH₃ act in concert to facilitate an NH₃ for PMe₃ exchange. Furthermore, H₂ NR and HNR₂ activation is demonstrated.

SUBMITTER: Dankert F 

PROVIDER: S-EPMC9400956 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature