Connecting Algal Polysaccharide Degradation to Formaldehyde Detoxification.
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ABSTRACT:
SUBMITTER: Brott S
PROVIDER: S-EPMC9400963 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
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Connecting Algal Polysaccharide Degradation to Formaldehyde Detoxification.
Brott Stefan S Thomas François F Behrens Maike M Methling Karen K Bartosik Daniel D Dutschei Theresa T Lalk Michael M Michel Gurvan G Schweder Thomas T Bornscheuer Uwe T UT
Chembiochem : a European journal of chemical biology 20220530 14
Formaldehyde is a toxic metabolite that is formed in large quantities during bacterial utilization of the methoxy sugar 6-O-methyl-d-galactose, an abundant monosaccharide in the red algal polysaccharide porphyran. Marine bacteria capable of metabolizing porphyran must therefore possess suitable detoxification systems for formaldehyde. We demonstrate here that detoxification of formaldehyde in the marine Flavobacterium Zobellia galactanivorans proceeds via the ribulose monophosphate pathway. Simu ...[more]
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