Para-Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes.

ABSTRACT: The para-selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF₂ is reported, with Et₃ N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set-up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.

SUBMITTER: Berger M 

PROVIDER: S-EPMC9401020 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature