Vibration-controlled transient elastography for noninvasive evaluation of liver steatosis.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) refers to a large spectrum of liver disorders and is the most common cause of metabolic liver disease. The current gold standard for diagnosing NAFLD is liver biopsy, which can lead to severe complications.

Purpose

Among the noninvasive diagnostic options, we chose to use a FibroScan and developed an algorithm applying the Voigt rheological model to assess the viscoelastic properties of the liver and evaluate its performance for the diagnosis of steatosis.

Methods

Twenty-two healthy volunteers and 20 patients with steatosis were included. For each subject, we used a modified FibroScan, whose data had been processed by our algorithm to separate the two viscoelastic components, stiffness μ, and viscosity η. The liver e

SUBMITTER: Pearson A 

PROVIDER: S-EPMC9401907 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature