Effect of probiotic bacteria on porcine rotavirus OSU infection of porcine intestinal epithelial IPEC-J2 cells.

ABSTRACT: Rotavirus infections in nursing or post-weaning piglets are known to cause diarrhea, which can lead to commercial losses. Probiotic supplementation is used as a prophylactic or therapeutic approach to dealing with microbial infections in humans and animals. To evaluate the effect of probiotic bacteria on porcine rotavirus infections, non-transformed porcine intestinal epithelial IPEC-J2 cells were used as an in vitro model, and three different procedures were tested. When cells were exposed to seven probiotics at concentrations of 10⁵, 10⁶, or 10⁷ CFU/mL for 16 h and removed before rotavirus challenge, infection reduction rates determined by flow cytometry were as follows: 15% (10⁶) and 18% (10⁵) for Bifidobacterium longum R0175, 15% (

SUBMITTER: Leblanc D 

PROVIDER: S-EPMC9402510 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature