The Peripheral Neuropathy Prevalence and Characteristics Are Comparable in People with Obesity and Long-Duration Type 1 Diabetes.

ABSTRACT:

Introduction

Peripheral neuropathy is reported in obesity even in the absence of hyperglycaemia.

Objective

To compare the prevalence and characterise the phenotype of peripheral neuropathy in people living with obesity (OB) and long-duration type 1 diabetes (T1D).

Patients and methods

We performed a prospective cross-sectional study of 130 participants including healthy volunteers (HV) (n = 28), people with T1D (n = 51), and OB (BMI 30-50 kg/m²) (n = 51). Participants underwent assessment of neuropathic symptoms (Neuropathy Symptom Profile, NSP), neurological deficits (Neuropathy Disability Score, NDS), vibration perception threshold (VPT) and evaluation of sural nerve conduction velocity and amplitude.

Results

Peripheral neuropathy was present in 43

SUBMITTER: Lim JZM 

PROVIDER: S-EPMC9402741 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature