Pubertal stage, sex and behaviour in neurodevelopmental disorders versus typical development: a cross-sectional study.

ABSTRACT:

Objective

To determine the association between pubertal stage, sex and behavioural profile across and within neurodevelopmental disorders (NDDs) compared with typically developing (TD) youth.

Methods

This was a cross-sectional study from the Province of Ontario Neurodevelopmental Disorders network, including children/youth with various NDDs and TD controls. Caregivers completed the Child Behavior Checklist (CBCL). Participants were grouped into three puberty stages: prepuberty (Tanner stage 1), early puberty (Tanner stages 2-3) and late puberty (Tanner stages 4-5). The association between pubertal stage and CBCL scores was assessed controlling for sex and diagnosis.

Results

The analysis included 1043 participants (male=733; 70.3%). A three-way interaction between pube

SUBMITTER: Penner M 

PROVIDER: S-EPMC9403165 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature