Clinical evaluation of a novel atlas-based PET/CT brain image segmentation and quantification method for epilepsy.

ABSTRACT:

Background

Positron emission tomography (PET)/computed tomography (CT) with [¹⁸F]fluorodeoxyglucose {[¹⁸F]FDG} has been shown to be an effective imaging method for the lateralization and localization of epilepsy. However, the efficacy of PET/CT image processing and analysis needs to be improved for clinical application. Our previous research proposed a novel atlas-based image method for PET brain image segmentation and quantification; in this study, we evaluated its effectiveness in clinical patients.

Methods

For image segmentation, a head anatomy template was registered to the subject image by integrating dual-modality image registration and landmark-constraint. The localizations of abnormalities were examined by quantitative comparison using the colle

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9403573 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature