Patterns of signs, symptoms, and laboratory values associated with Zika, dengue, and undefined acute illnesses in a dengue endemic region: Secondary analysis of a prospective cohort study in southern Mexico.

ABSTRACT:

Objectives

Dengue and Zika infections cause illnesses with overlapping clinical manifestations. The aim of this study was to explore the association of each of these infections with single or grouped clinical and laboratory parameters.

Methods

Clinical and laboratory data were collected prospectively from a cohort of patients seeking care for symptoms meeting the Pan American Health Organization's modified case-definition criteria for probable Zika virus infection. Zika and dengue were diagnosed with RT-PCR. The relationship of clinical characteristics and laboratory data with Zika, dengue, and undefined acute illness (UAI) was examined.

Results

In the univariate models, localized rash and maculopapular exanthema were associated with Zika infection. Generalized rash,

SUBMITTER: Hunsberger S 

PROVIDER: S-EPMC9403947 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature