Chicken Protein S Gene Regulates Adipogenesis and Affects Abdominal Fat Deposition.

ABSTRACT: (1) Background: Excessive abdominal fat deposition in broilers not only causes feed waste but also leads to a series of metabolic diseases. It has gradually become a new breeding goal of the broiler industry to improve growth rates and to reduce abdominal fat rates. In a previous study, PROS1 was highly expressed in low-abdominal fat broilers, suggesting a potential role in broilers adipogenesis. However, the function of PROS1 in preadipocytes and its association with abdominal fat traits need to be characterized. (2) Methods: qRT-PCR and Western Blot were used to quantify gene expression at the RNA and protein levels; flow cytometry and EdU were carried out to detect cell proliferation; and a GLM analysis was used to determine the association between PROS1 SNPs and ca

SUBMITTER: Guo L 

PROVIDER: S-EPMC9404415 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature