Labdane-type Diterpenes from Pinus eldarica Needles and Their Anti-Helicobacter pylori Activity.

ABSTRACT: Pinus eldarica is a medicinal tree used in traditional herbal medicine for the treatment of bronchial asthma and various skin diseases. As part of our ongoing search for bioactive phytochemicals with novel structures in natural products, we performed a phytochemical analysis of the methanol (MeOH) extract from P. eldarica needles collected in Iran. Phytochemical investigation of the MeOH extract, aided by liquid chromatography-mass spectrometry-based analysis, resulted in the isolation and identification of three labdane-type diterpenes (1-3), including a new and relatively unique norlabdane-type diterpene with a peroxide moiety, eldaricoxide A (1). The chemical structures of the isolated labdane-type diterpenes were elucidated by analyzing the spectroscopic dat

SUBMITTER: Jeong SY 

PROVIDER: S-EPMC9404486 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature