Structure-Activity Relationship Study of Xanthoxyline and Related Small Methyl Ketone Herbicides.

ABSTRACT: Xanthoxyline (1), a small natural methyl ketone, was previously reported as a plant growth inhibitor. In this research, related methyl ketones bearing electron-donating and electron-withdrawing groups, together with heteroaromatics, were investigated against seed germination and seedling growth of Chinese amaranth (Amaranthus tricolor L.) and barnyard grass [Echinochloa crus-galli (L.) Beauv]. The structure-activity relationships (SARs) of methyl ketone herbicides were clarified, and which types and positions of substituents were crucially important for activity were also clarified. Indole derivatives, namely, 3-acetylindole (43) and 3-acetyl-7-azaindole (44) were found to be the most active methyl ketones that highly suppressed plant growth at low concen

SUBMITTER: Chotpatiwetchkul W 

PROVIDER: S-EPMC9404509 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature