Effects of dexmedetomidine on cardiac electrophysiology in patients undergoing general anesthesia during perioperative period: a randomized controlled trial.

ABSTRACT:

Background

Dexmedetomidine has controversial influence on cardiac electrophysiology. The aim of this study was to explore the effects of dexmedetomidine on perioperative cardiac electrophysiology in patients undergoing general anesthesia.

Methods

Eighty-one patients were randomly divided into four groups: groups D₁, D₂, D₃ receiving dexmedetomidine 1, 1, 0.5 μg/kg over 10 min and 1, 0.5, 0.5 μg/kg/h continuous infusion respectively, and control group (group C) receiving normal saline. Twelve-lead electrocardiograms were recorded at the time before dexmedetomidine/normal saline infusion (T₁), loading dose finish (T₂), surgery ending (T₆), 1 h (T₇) after entering PACU, 24 h (T₈), 48 h (T

SUBMITTER: Tan C 

PROVIDER: S-EPMC9404616 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature