Efficacy of pramipexole on quality of life in patients with Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Background

Quality of life (QoL) in patients with Parkinson's disease (PD) is increasingly used as an efficacy outcome in clinical studies of PD to evaluate the impact of treatment from the patient's perspective. Studies demonstrating the treatment effect of pramipexole on QoL remain inconclusive. This study aims to evaluate the effect of pramipexole on QoL in patients with PD by conducting a systematic review and meta-analysis of existing clinical trials.

Methods

A systematic literature search of PubMed, Embase and the Cochrane Library was performed from inception to 30 April 2022 to identify randomised, placebo-controlled trials of patients with idiopathic PD receiving pramipexole, who reported a change from baseline in their QoL as measured by the 39-item Parkinson's Dise

SUBMITTER: Li T 

PROVIDER: S-EPMC9404654 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature