Genomic Analysis of Acinetobacter baumannii Isolates Carrying OXA-23 and OXA-58 Genes from Animals Reveals ST1 and ST25 as Major Clonal Lineages.

ABSTRACT: Acinetobacter baumannii is increasingly being recognized as a relevant pathogen for animals with a putative zoonotic impact. This study aimed at identifying and characterizing carbapenemase-producing A. baumannii from animals. Among 503 A. baumannii, mainly isolated from dogs/cats (75.7%) between 2013 and 2018, 42 isolates from 22 veterinary clinics (VCs) harboured bla_OXA-58 (n = 29) or bla_OXA-23 (n = 13). The bla_OXA-58 gene was located on plasmids (11.4-21.1 kb) within different genetic surroundings (patterns A-D). Bla_OXA-23 was embedded in Tn2006 on the chromosome (n = 4; pattern a) or Tn2008 on plasmids (n = 9; 41.2-71.3 kb; patterns b-e). The predominan

SUBMITTER: Jacobmeyer L 

PROVIDER: S-EPMC9404926 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature