Ontology highlight
ABSTRACT:
SUBMITTER: Ke S
PROVIDER: S-EPMC9405870 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Ke Shuai S Liu Zelin Z Wang Qinghua Q Zhai Guanzhong G Shao Haoren H Yu Xi X Guo Jia J
Cancers 20220813 16
Prostate cancer (PCa) is one of the most common cancers and is the second leading cause of mortality in men. Studies exploring novel therapeutic methods are urgently needed. FAM107A, a coding gene located in the short arm of chromosome3, is generally downregulated in PCa and is associated with a poor prognosis. However, the downregulation of FAM107A in PCa and the mechanism of its action remain challenging to determine. This investigation found that downregulation of FAM107A expression in PCa wa ...[more]