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Oligometastatic Head and Neck Cancer: Challenges and Perspectives.


ABSTRACT: A minority of patients with metastatic head and neck squamous cell carcinoma (HNSCC) present with oligometastatic disease. Oligometastasis not only reflects a disease state, but might also present an opportunity for cure in the metastatic setting. Radical ablation of all oligometastatic sites may confer prolonged survival and possibly achieve cure in some patients. However, substantial debate remains about whether patients with oligometastatic disease could benefit from curative intent therapy or whether aggressive treatments expose some patients to futile toxicity. Optimal selection of patients, carefully balancing the currently known prognostic factors against the risks of toxicity is critical. Emerging evidence suggests that patients with a limited burden of disease, viral-related phary

SUBMITTER: Bahig H 

PROVIDER: S-EPMC9405984 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature