Data Processing of SPR Curve Data to Maximize the Extraction of Changes in Electrochemical SPR Measurements.

ABSTRACT: We developed a novel measuring and data-processing method for performing electrochemical surface plasmon resonance (EC-SPR) on sensor surfaces for which detecting a specific SPR angle is difficult, such as a polymer having a non-uniform thickness with coloration. SPR measurements are used in medicine and basic research as an analytical method capable of molecular detection without labeling. However, SPR is not good for detecting small molecules with small refractive index changes. The proposed EC-SPR, which combines SPR measurements with an electrochemical reaction, makes it possible to measure small molecules without increasing the number of measurement steps. A drawback of EC-SPR is that it is difficult to detect a specific SPR angle on electron mediators, and it was found that it may no

SUBMITTER: Inoue S 

PROVIDER: S-EPMC9406148 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature