A Review of Adrenomedullin in Pediatric Patients: A Useful Biomarker.

ABSTRACT: Adrenomedullin has several properties. It acts as a potent vasodilator, has natriuretic effects, and reduces endothelial permeability. It also plays a role in initiating the early hyperdynamic phase of sepsis. Since its discovery, many articles have been published studying the uses and benefits of this biomarker. The aim of this review is to determine the usefulness of adrenomedullin in pediatric patients. Relevant studies covering adrenomedullin in pediatrics (<18 years) and published up until August 2021 were identified through a search of MEDLINE, PubMed, Embase, Web of Science, Scopus, and Cochrane. Seventy studies were included in the present review, most of them with a low level of evidence (IV to VI). Research on adrenomedullin has primarily been related to infection and the card

SUBMITTER: Sole-Ribalta A 

PROVIDER: S-EPMC9406574 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature