Synthetic Arterial Spin Labeling MRI of the Kidneys for Evaluation of Data Processing Pipeline.

ABSTRACT: Accurate quantification of perfusion is crucial for diagnosis and monitoring of kidney function. Arterial spin labeling (ASL), a completely non-invasive magnetic resonance imaging technique, is a promising method for this application. However, differences in acquisition (e.g., ASL parameters, readout) and processing (e.g., registration, segmentation) between studies impede the comparison of results. To alleviate challenges arising solely from differences in processing pipelines, synthetic data are of great value. In this work, synthetic renal ASL data were generated using body models from the XCAT phantom and perfusion was added using the general kinetic model. Our in-house developed processing pipeline was then evaluated in terms of registration, quantification, and segmentation using the

SUBMITTER: Brumer I 

PROVIDER: S-EPMC9406826 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature