Ontology highlight
ABSTRACT:
SUBMITTER: Malavolta M
PROVIDER: S-EPMC9406876 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Malavolta Marco M Giacconi Robertina R Piacenza Francesco F Strizzi Sergio S Cardelli Maurizio M Bigossi Giorgia G Marcozzi Serena S Tiano Luca L Marcheggiani Fabio F Matacchione Giulia G Giuliani Angelica A Olivieri Fabiola F Crivellari Ilaria I Beltrami Antonio Paolo AP Serra Alessandro A Demaria Marco M Provinciali Mauro M
Cells 20220812 16
Cellular senescence is a hallmark of aging and a promising target for therapeutic approaches. The identification of senescent cells requires multiple biomarkers and complex experimental procedures, resulting in increased variability and reduced sensitivity. Here, we propose a simple and broadly applicable imaging flow cytometry (IFC) method. This method is based on measuring autofluorescence and morphological parameters and on applying recent artificial intelligence (AI) and machine learning (ML ...[more]