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Unique Growth Pattern Presentation of a Papillary Renal Cell Carcinoma.


ABSTRACT: Papillary renal cell carcinoma (PRCC) is defined by the WHO 2022 classification as a malignant tumor derived from the renal tubular epithelium. However, the WHO 2016 classification subdivided PRCC into two types, with type 1 PRCC showing papillae covered by a single layer of neoplastic cells, and type II PRCC, which can show multiple types of histologies and is more aggressive. The WHO 2022 classification eliminated the subcategorization of PRCC. Here, we present a histopathological case study with a 4-year follow-up diagnosed in 2018 as type I PRCC (WHO 2016) with intra-pyelocalyceal growth pattern in a 59-year-old male patient with a history of Type II diabetes mellitus, left-sided renal-ureteral lithiasis, and benign hypertrophy of the prostate. Microscopically the tumor was composed of

SUBMITTER: Harich OO 

PROVIDER: S-EPMC9406930 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature