A new class of cobalamin transport mutants (btuF) provides genetic evidence for a periplasmic binding protein in Salmonella typhimurium.

ABSTRACT: No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters.

SUBMITTER: Van Bibber M 

PROVIDER: S-EPMC94070 | biostudies-literature | 1999 Sep

REPOSITORIES: biostudies-literature