Benzene and NO₂ Exposure during Pregnancy and Preterm Birth in Two Philadelphia Hospitals, 2013-2017.

ABSTRACT: Infants born preterm are at risk of neonatal morbidity and mortality. Preterm birth (PTB) can be categorized as either spontaneous (sPTB) or medically indicated (mPTB), resulting from distinct pathophysiologic processes such as preterm labor or preeclampsia, respectively. A growing body of literature has demonstrated the impacts of nitrogen dioxide (NO₂) and benzene exposure on PTB, though few studies have investigated how these associations may differ by PTB subtype. We investigated the associations of NO₂ and benzene exposure with sPTB and mPTB among 18,616 singleton live births at two Philadelphia hospitals between 2013 and 2017. Residential NO₂ exposure was estimated using a land use regression model and averaged over the patient's full pregnancy. Benze

SUBMITTER: Escoto KM 

PROVIDER: S-EPMC9408580 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature