Nontargeted Analysis Study Reporting Tool: A Framework to Improve Research Transparency and Reproducibility.

ABSTRACT: Non-targeted analysis (NTA) workflows using mass spectrometry are gaining popularity in many disciplines, but universally accepted reporting standards are nonexistent. Current guidance addresses limited elements of NTA reporting-most notably, identification confidence-and is insufficient to ensure scientific transparency and reproducibility given the complexity of these methods. This lack of reporting standards hinders researchers' development of thorough study protocols and reviewers' ability to efficiently assess grant and manuscript submissions. To overcome these challenges, we developed the NTA Study Reporting Tool (SRT), an easy-to-use, interdisciplinary framework for comprehensive NTA methods and results reporting. Eleven NTA practitioners reviewed eight published articles covering e

SUBMITTER: Peter KT 

PROVIDER: S-EPMC9408805 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature