GcvB Regulon Revealed by Transcriptomic and Proteomic Analysis in Vibrio alginolyticus.

ABSTRACT: Vibrio alginolyticus is a widely distributed marine bacterium that is a threat to the aquaculture industry as well as human health. Evidence has revealed critical roles for small RNAs (sRNAs) in bacterial physiology and cellular processes by modulating gene expression post-transcriptionally. GcvB is one of the most conserved sRNAs that is regarded as the master regulator of amino acid uptake and metabolism in a wide range of Gram-negative bacteria. However, little information about GcvB-mediated regulation in V. alginolyticus is available. Here we first characterized GcvB in V. alginolyticus ZJ-T and determined its regulon by integrated transcriptome and quantitative proteome analysis. Transcriptome analysis revealed 40 genes differentially expressed (DEGs) between wil

SUBMITTER: Liu B 

PROVIDER: S-EPMC9409037 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature