A prevalence-based transmission model for the study of the epidemiology and control of soil-transmitted helminthiasis.

ABSTRACT: Much effort has been devoted by the World Health Organization (WHO) to eliminate soil-transmitted helminth (STH) infections by 2030 using mass drug administration targeted at particular risk groups alongside the availability to access water, sanitation and hygiene services. The targets set by the WHO for the control of helminth infections are typically defined in terms of the prevalence of infection, whereas the standard formulation of STH transmission models typically describe dynamic changes in the mean-worm burden. We develop a prevalence-based deterministic model to investigate the transmission dynamics of soil-transmitted helminthiasis in humans, subject to continuous exposure to infection over time. We analytically determine local stability criteria for all equilibria and find bifurc

SUBMITTER: Chong NS 

PROVIDER: S-EPMC9409602 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature