Effects of Fasting and Lifestyle Modification in Patients with Metabolic Syndrome: A Randomized Controlled Trial.

ABSTRACT:

Background

Lifestyle interventions, such as fasting, diet, and exercise, are increasingly used as a treatment option for patients with metabolic syndrome (MS). This study assesses the efficacy and safety of fasting followed by lifestyle modification in patients with MS compared to lifestyle modification only.

Methods

Single-blind, multicenter, parallel, randomized controlled trial in two German tertiary referral hospitals in metropolitan areas.

Interventions

(a) 5-day fasting followed by 10 weeks of lifestyle modification (modified DASH diet, exercise, mindfulness; n = 73); (b) 10 weeks of lifestyle modification only (n = 72).

Main outcomes and measures

Co-primary outcomes were ambulatory systolic blood pressure and the homeostasis model assessmen

SUBMITTER: Cramer H 

PROVIDER: S-EPMC9410059 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature