The Synthesis and Assembly of a Truncated Cyanophage Genome and Its Expression in a Heterogenous Host.

ABSTRACT: Cyanophages play an important role in regulating the dynamics of cyanobacteria communities in the hydrosphere, representing a promising biological control strategy for cyanobacterial blooms. Nevertheless, most cyanophages are host-specific, making it difficult to control blooming cyanobacteria via single or multiple cyanophages. In order to address the issue, we explore the interaction between cyanophages and their heterologous hosts, with the aim of revealing the principles of designing and constructing an artificial cyanophage genome towards multiple cyanobacterial hosts. In the present study, we use synthetic biological approaches to assess the impact of introducing a fragment of cyanophage genome into a heterologous cyanobacterium under a variety of environmental conditions. Based on a

SUBMITTER: Liu S 

PROVIDER: S-EPMC9410186 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature