Two Independent Capsules Surrounding a Single Textured Implant in Ehlers-Danlos Syndrome.

ABSTRACT: Textured breast implants are associated with prolonged inflammation leading to increased risk for complications such as the development of anaplastic large cell lymphoma. The underlying molecular mechanisms that drive increased inflammation toward textured implants (compared with smooth implants) remain poorly understood. Here, we present the first known case of a patient with Ehlers-Danlos syndrome (EDS) who developed two independent fibrotic capsules around a single textured silicone implant. The patient was found to have one internal capsule tightly adherent to the implant and a second external capsule that was attached to the surrounding tissue. We observed that the internal implant-adherent capsule was composed of a highly aligned and dense collagen network, completely atypical for ED

SUBMITTER: Padmanabhan J 

PROVIDER: S-EPMC9410635 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature