Gadolinium-based contrast agents for imaging of the central nervous system: A multicenter European prospective study.

ABSTRACT: Contrast-enhanced MR (CE-MR) imaging is required to improve lesion detection and characterization and to increase diagnostic confidence. This study aims to evaluate the safety, effectiveness, and usage patterns of recently introduced ClariscanTM (gadoterate meglumine) and other macrocyclic gadolinium-based contrast agents (GBCAs) used for magnetic resonance imaging (MRI) of the central nervous system (CNS). Data was obtained from a European multicenter, prospective, observational postmarketing study that included pediatric and adult patients undergoing contrast-enhanced MRI with a GBCA used in routine clinical practice. Safety data was collected by spontaneous patient adverse event (AE) reporting. Effectiveness was assessed via changes in radiological diagnosis, diagnostic confidence, and

SUBMITTER: Heshmatzadeh Behzadi A 

PROVIDER: S-EPMC9410688 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature