Identification of a functional fur gene in Bradyrhizobium japonicum.

ABSTRACT: The recent identification of the iron response regulator (Irr) in Bradyrhizobium japonicum raised the question of whether the global regulator Fur is present in that organism. A fur gene homolog was isolated by the functional complementation of an Escherichia coli fur mutant. The B. japonicum Fur bound to a Fur box DNA element in vitro, and a fur mutant grown in iron-replete medium was derepressed for iron uptake activity. Thus, B. japonicum expresses at least two regulators of iron metabolism.

SUBMITTER: Hamza I 

PROVIDER: S-EPMC94108 | biostudies-literature | 1999 Sep

REPOSITORIES: biostudies-literature