Statin Use in Older Adults for Primary Cardiovascular Disease Prevention Across a Spectrum of Cardiovascular Risk.

ABSTRACT:

Background

There remains uncertainty regarding optimal primary atherosclerotic cardiovascular disease (ASCVD) prevention practices for older adults.

Objective

To assess statin treatment patterns and incident ASCVD among older patients for primary prevention across the spectrum of ASCVD risk.

Design

Retrospective cohort study of participants without ASCVD aged 65-79 years. Patients were stratified by age (65-69, 70-75, > 75 years) and 10-year ASCVD risk category (low/borderline, intermediate, high) based on the Pooled Cohort Equations. Multivariable logistic regressions were used to identify predictors of moderate- or high-intensity statin prescriptions. Cox proportional models were used to estimate hazard ratios (HRs) for incident ASCVD.

Participants

Patients a

SUBMITTER: Sarraju A 

PROVIDER: S-EPMC9411428 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature