Postoperative day 1 serum cystatin C level predicts postoperative delayed graft function after kidney transplantation.

ABSTRACT:

Background

Delayed graft function (DGF) commonly occurs after kidney transplantation, but no clinical predictors for guiding post-transplant management are available.

Materials and methods

Data including demographics, surgery, anesthesia, postoperative day 1 serum cystatin C (S-CysC) level, kidney functions, and postoperative complications in 603 kidney transplant recipients who met the enrollment criteria from January 2017 to December 2018 were collected and analyzed to form the Intention-To-Treat (ITT) set. All perioperative data were screened using the least absolute shrinkage and selection operator. The discrimination, calibration, and clinical effectiveness of the predictor were verified with area under curve (AUC), calibration plot, clinical decision curve, and impact

SUBMITTER: Li Y 

PROVIDER: S-EPMC9411520 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature