Exploration of cerebral hemodynamic pathways through which large artery function affects neurovascular coupling in young women.

ABSTRACT:

Background

The interactions between large artery function and neurovascular coupling (NVC) are emerging as important contributors to cognitive health. Women are disproportionally affected by Alzheimer's disease and related dementia later in life. Understanding large artery correlates of NVC in young women may help with preservation of cognitive health with advancing age.

Purpose

To explore the association between large artery function, NVC and cognitive performance in young women.

Methods

Vascular measurements were made in 61 women (21 ± 4 yrs) at rest and during a cognitive challenge (Stroop task). Transcranial Doppler was used to measure left middle cerebral artery (MCA) maximum velocity (V_max), mean velocity (V_mean), and pulsatility index (PI)

SUBMITTER: Cilhoroz BT 

PROVIDER: S-EPMC9411931 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature